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Oxycodone and Roxicodone are prescription opioid medications used to manage moderate to severe pain, but they differ mainly in formulation. Oxycodone is the active opioid ingredient found in various products, including both immediate-release (IR) and extended-release (ER) versions. Roxicodone is a brand name for immediate-release oxycodone, designed to provide faster pain relief for short periods. Because it acts quickly, Roxicodone may be used for sudden or breakthrough pain, while ER oxycodone offers longer-lasting control. Both medications carry risks of dependence, overdose, and side effects, so they must be used exactly as prescribed under medical supervision.

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Both forms of the medication are effective and safe and they are also both relatively effective in alleviating the anxiety symptoms that commonly co-occur with depression. Adults and children 12 years of age and older—10 milligrams (mg) once a day, taken either in the morning or evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 20 mg per day. Older adults—10 mg once a day, taken either in the morning or evening.

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