Hydrocodone is a powerful semi-synthetic opioid analgesic used primarily to treat moderate to severe pain and as a cough suppressant. It works by binding to opioid receptors in the brain and spinal cord, altering the perception of pain and emotional response to it. Hydrocodone is often combined with non-opioid pain relievers like acetaminophen (as in Hydrocodone/APAP combinations such as Norco, Vicodin, or Lortab) or ibuprofen to enhance its pain-relieving effects.