Oxycodone is a powerful prescription opioid pain reliever used to manage moderate to severe pain. It works by changing the way your brain and nervous system respond to pain signals, helping reduce the sensation of pain. Oxycodone is often prescribed after surgery, injury, or for chronic conditions where other pain treatments haven’t been effective. As an opioid, oxycodone binds to receptors in the brain that control pain and emotions. While highly effective for pain management, it also comes with a serious risk of misuse, addiction, and dependence—especially when not taken exactly as prescribed.