Lorazepam Vs Klonopin are benzodiazepines with varying durations and potencies. In general, 0.5 mg of Klonopin is about the same as 1 mg of Lorazepam. Lorazepam acts more quickly for acute anxiety, while Klonopin lasts longer, making it helpful for long-term comfort. Under medical supervision, dosage must always be customized.