https://medixway.com/pain-relief/hydrocodone/ Hydrocodone is a powerful prescription opioid medication primarily used to relieve moderate to severe pain. It works by acting on the brain and central nervous system to change how the body perceives pain. Hydrocodone is often combined with non-opioid pain relievers like acetaminophen or ibuprofen to increase its effectiveness.Common brand names for hydrocodone combinations include Vicodin, Norco, and Lortab. It is typically prescribed after surgery, for injury-related pain, or for chronic pain conditions that do not respond to weaker painkillers.