PNC-27 is a synthetic research peptide developed to investigate a unique approach to cancer-cell targeting. Early studies suggest that it may bind to a protein called HDM-2, which is often overexpressed on the membranes of certain cancer cells but not typically present on healthy cells. By attaching to this protein, PNC-27 may help form pores in the tumor cell membrane, a process researchers believe could lead to cell disruption while leaving normal tissues largely unaffected. Its proposed selectivity has sparked scientific interest, especially in exploring how peptides might differentiate between malignant and non-malignant cells. Although findings are still preliminary and limited to laboratory environments, PNC-27 continues to be studied for its potential relevance in future cancer research. This expanded description explains its hypothesized mechanism, highlights why it draws attention in experimental oncology, and clarifies that it remains strictly a research-only compound without proven clinical applications.