Meridia (sibutramine) is an affordable weight loss medication available online, acting as a serotonin and norepinephrine reuptake inhibitor to suppress appetite and promote fat loss. Clinical trials show it aids 5-10% body weight reduction over 6-12 months when combined with diet, reducing waist circumference and improving lipid profiles. Patients losing at least 4 pounds in the first 4 weeks often achieve sustained results. However, it was withdrawn in many markets due to cardiovascular risks; consult a doctor before use.