NAD+ peptides are becoming a focal point in modern biological research due to their potential impact on cellular energy regulation, mitochondrial health, and overall muscle function. As NAD+ levels naturally decline with age, scientists are investigating whether supporting this pathway through peptide-based approaches may influence muscle strength, endurance, and recovery capacity. Emerging studies suggest possible roles in enhancing ATP production, promoting healthier mitochondrial activity, and supporting cellular repair mechanisms all of which are essential for maintaining optimal muscle performance. This expanded analysis explores the latest research developments, the proposed mechanisms behind NAD+ peptide activity, and how these compounds may be shaping new directions in muscle physiology investigations. While findings are still early and primarily preclinical, ongoing scientific exploration continues to build a deeper understanding of how NAD+ peptides might contribute to muscle health, metabolic efficiency, and long-term cellular vitality.