Oxycodone and Roxicodone are both opioid medications used to manage moderate to severe pain, but they differ slightly in formulation and use. Oxycodone is available in immediate-release and extended-release forms, often prescribed for ongoing or chronic pain. Roxicodone is a brand of immediate-release oxycodone, typically used for short-term or breakthrough pain. Both medications carry risks of dependence, misuse, and side effects such as drowsiness, nausea, and constipation. Choosing the appropriate medication depends on pain severity, duration, and individual health factors. Safe use under a healthcare provider’s supervision is essential to maximize pain relief while minimizing risks.