To make Levitra (vardenafil) more effective, you can optimize how and when you take it, make certain lifestyle adjustments, and consult your doctor about dosage or alternative treatments. For best results, take Levitra approximately 60 minutes before sexual activity. This allows sufficient time for the medication to be absorbed and work properly. Levitra is not an aphrodisiac and requires sexual stimulation to produce an erection. Foreplay and emotional connection with your partner are essential to trigger the natural physiological response required for an erection.