Selank is a synthetic peptide derived from the immunomodulatory fragment of tuftsin and has drawn growing interest in infection-related research. Scientific investigations have explored Selank’s potential influence on immune signaling pathways, particularly its role in modulating cytokine activity, neuroimmune communication, and stress-associated immune responses. These properties have positioned Selank as a useful research compound for studying how immune balance may affect susceptibility, progression, and resolution of infectious processes. Current studies examine Selank’s interactions with innate and adaptive immune mechanisms, including its effects on interferon regulation, inflammatory mediators, and antimicrobial defense pathways in experimental models. Researchers are also assessing how Selank’s anxiolytic and neuroregulatory characteristics may indirectly shape immune function during infection-related stress states.