Hydrocodone M365 is a combination pain-relieving prescription pill for the relief of moderate to severe pain. It consists of Hydrocodone, an opioid painkiller and acetaminophen, a non-opioid painkiller which are usually applied in treating moderately to severely painful surgery, pain due to injury, or malignancy (cancer) pain. White m365 pill is sold using different brand names and, as a verifier of the strength of the product whether branded or generic, is imprinted with “M365”. It is important that individuals who experience a high pain profile know how it works, the medical use of the medication, adverse events that can come from it and what safe medication handling can help all patients, and their caregivers, make better-informed choices about which medications are appropriate for them.