Scientific research on peptides and pain mechanisms has gained increasing attention due to peptides’ role as signaling molecules that influence neurological, inflammatory, and cellular processes. Peptides are short chains of amino acids that may interact with receptors, enzymes, and ion channels involved in nociception—the biological process through which pain is perceived. Researchers have investigated naturally occurring peptides such as endorphins, enkephalins, and substance P, which appear to play significant roles in modulating pain signaling within the central and peripheral nervous systems. According to organizations like the International Association for the Study of Pain, understanding these molecular interactions is essential for advancing scientific knowledge of both acute and chronic pain pathways.