It is difficult to compare the dangers of Heroin and Cocaine, because both drugs affect the body in completely different ways. Heroin is a powerful depressant that slows down our nervous system, which results in severe breathin problem. On the other hand, cocaine is a powerful stimulant that puts extreme stress on the cardiovascular stress, increasing the chance of heart attacks, strokes, or seizures. In case of immediate overdose death, heroin is much more potent than cocaine. Cocaine’s damage is often internal and cumulative, silently straining the heart. Ultimately, both are life-threatening, but heroin has a higher chance of shutting the body down.