Yes, Vicodin can cause of headaches. If you or your loved one is using Vicodin for some medical reason, and you feel like headache, then contact your healthcare provider. Because bearing this pain can become a big problem in the future. It also happens because of withdrawal symptoms, so don’t stop your medication without asking your doctor. All problems have a treatment or solution, and overcoming withdrawal symptoms is time taking process, but not impossible. To overcome withdrawal symptoms, many rehab centers are providing evidence-based therapies and medical detoxification. So stay safe and live a happy life with the right cure.