Buy Hydrocodone Online Now! Secure pills are guaranteed by authorities. 24/7 customer support, fast shipping, and discreet packaging. Hydrocodone is a painkiller in the opioid family (related to morphine). Acetaminophen is an over-the-counter medicine. Hydrocodone is an opioid pain reliever that is used to treat moderate and severe pain. It affects the brain and nervous system and can be used alone or with other pain medicines. Hydrocodone works differently from other opioids.