Naloxone is added to deter misuse of the medication as it can trigger withdrawal symptoms if someone tries to inject it to get high. Suboxone is a prescription medication that combines two active ingredients: buprenorphine and naloxone. Buprenorphine is a partial opioid agonist, meaning it activates the opioid receptors in the brain but to a lesser extent than full opioids like heroin or oxycodone.