Vicodin is a prescription medication commonly prescribed for pain relief. It contains a combination of hydrocodone, an opioid pain reliever, and acetaminophen, a non-opioid pain reliever. Typically, it’s used to treat moderate to severe pain, especially after surgery or injury. Due to the opioid component, Vicodin has addictive potential and is a controlled substance, meaning it is illegal to purchase Vicodin without a prescription in most places