Opana ER 40 mg is a powerful, extended-release opioid medication that contains oxymorphone. It's typically prescribed for managing severe chronic pain that needs ongoing, long-term treatment. This medication is crafted to deliver steady and enduring pain relief, but it must be taken under close medical supervision because of the potential risks, including addiction, overdose, and serious side effects. In this guide, we’ll cover how to use it properly, the recommended dosage, and key safety tips to keep in mind.