Click Here To Know More: https://mayomeds.com/faq/does-zolpidem-lower-blood-pressure/ Zolpidem primarily functions as a sedative hypnotic, targeting the brain’s GABA receptors to promote sleep. Zolpidem comes under the generic name Ambien, which is not commonly used to treat hypertension and is not categorized as a blood pressure medicine. However, certain research and case reports indicate that Zolpidem’s relaxing effects on the central nervous system, which might result in a reduced heart rate and vascular resistance, may produce a modest drop in blood pressure.