Treatment of muscle spasms and musculoskeletal conditions includes both Tizanidine and Soma. Tizanidine is a medicine that treats the problem of spasm, cramps, tightness, and sclerosis. It is a scientific medicine. Soma is a medication to treat musculoskeletal spasms. Both medications treat the same problems that happen in the body. So in this article, we will discuss the differences between them, like their risks, effects, and composition between Tizanidine vs Soma.