When it comes to treating panic disorder, both Klonopin (clonazepam) and Lorazepam (Ativan) are commonly prescribed benzodiazepines. Each has its own onset time, duration of action, and potential side effects. Klonopin is often preferred for longer-lasting relief, while Lorazepam may be better for acute episodes. However, effectiveness and tolerance can vary from person to person. This article compares both medications to help determine which might be the better fit for managing panic disorder.