Also pain is viewed negatively, it is not possible to get rid of it totally but those people who manage chronic pain effectively lead a happy life. Nowadays, doctors often prescribe nonsteroidal anti-inflammatory drugs (NSAIDs) to get rid of discomfort and inflammation. Both the drugs hydrocodone and diclofenac decrease inflammation and block the enzymes that cause pain and swelling. They differ in their formulations, class of family, clinical applications, and potency levels.