Hydrocodone, a prescription opioid for pain relief, stays in the body for different durations depending on the testing method. It can be detected in blood for about 24 hours, in urine for 3–4 days, and in saliva for 12–36 hours. Factors such as dosage, metabolism, frequency of use, and overall health can affect detection times. Understanding these timelines is important for safe use, medical testing, and recovery planning.