Adderall (amphetamine/dextroamphetamine) is a stimulant commonly prescribed for ADHD, while Wellbutrin (bupropion) is an antidepressant that affects dopamine and norepinephrine. Some doctors may prescribe them together to manage ADHD with coexisting depression or to enhance focus and mood. However, combining Adderall and Wellbutrin can increase risks such as anxiety, insomnia, elevated blood pressure, or seizures in susceptible individuals. Understanding how Adderall and Wellbutrin work, their benefits, and possible interactions is essential before using them together.