Most true antibiotics require a prescription, but certain over-the-counter (OTC) products have antibacterial properties that can help with minor cuts, scrapes, or skin infections. These include topical options like Neosporin, Polysporin, and bacitracin ointments. While helpful for external use, OTC antibiotics cannot treat internal infections such as strep throat or bronchitis. Understanding over-the-counter antibiotics helps people know when self-care is appropriate and when prescription medication or a doctor’s visit is necessary.