Like Klonopin, Lorazepam, and branded Ativan also suppress the brain’s activity by enhancing GABA-A receptors. They also more or less differ from each other, for one, Clonazepam has a half-life of 30-40 hours while Lorazepam has 10-20. The latter tends to serve to treat acute anxiety and during some medical procedures. On the other hand, clonazepam is more effective for seizures and panic disorder. With Clonazepam and lorazepam as the two better-known names, these drugs are both from the benzodiazepine sub-group. While both of them are effective to a certain degree, the two of them differ greatly in the length of time they are effective, their mechanisms of action, and what conditions are best treated with them. patients as well as other medical professionals to a certain degree.