Tramadol, along with Naproxen, is are medication prescribed widely for the relief of pain. Are you worried about relieving pain safely? Don’t worry, we have a solution for you. Tramadol belongs to the opioid analgesic class of drugs, and it works on the central nervous system, so it can manage moderate to severe pain. Naproxen, an anti-inflammatory non-steroidal (NSAID), also reduces pain and inflammation.