When comparing Oxycodone vs Ibuprofen, understanding their differences is crucial for safe and effective pain management. Oxycodone is a prescription opioid used for moderate to severe pain, especially after surgery or injury. It works by blocking pain signals in the brain and nervous system, providing strong relief but also carrying a higher risk of dependence and side effects like drowsiness or nausea. Ibuprofen, on the other hand, is an over-the-counter nonsteroidal anti-inflammatory drug (NSAID) used for mild to moderate pain, inflammation, or fever.