Norco 5-325 mg is a prescription pain medication used to treat moderate to moderately severe pain. The name “5-325” refers to the strength of its two active ingredients: Hydrocodone 5 mg – an opioid pain reliever that changes how the brain perceives pain. Acetaminophen 325 mg – a non-opioid pain reliever that also helps reduce fever and enhances pain control. Doctors may prescribe Norco after surgery, injury, or for certain medical conditions when other pain relievers aren’t effective enough. It usually starts working within 30–60 minutes. Because it contains an opioid, Norco carries risks such as drowsiness, nausea, constipation, dependence, and breathing problems. It must be taken only with a valid prescription and exactly as directed by a healthcare professional. It’s not meant for long-term use unless closely monitored by a doctor