Norco 10-325 mg is a prescription medication used to treat moderate to severe pain when other pain treatments are not effective. It combines hydrocodone bitartrate (10 mg) and acetaminophen (325 mg). Hydrocodone is an opioid pain reliever that works by affecting pain signals in the brain and nervous system, while acetaminophen is a non-opioid analgesic that helps reduce pain and fever and enhances the overall pain-relieving effect.