???? Unlock 25% OFF – Instant Order Today! ???? Vicodin is a well-known prescription medication used to manage moderate to severe pain when other treatments are not effective. It combines hydrocodone, an opioid pain reliever, with acetaminophen, a non-opioid analgesic that enhances pain control. Because of its strength and potential risks, Vicodin is classified as a controlled substance and must be used only under the supervision of a licensed healthcare provider.