The most straightforward way to talk to a live person is by calling their customer service hotline. American Airlines’s main customer service number is 1-800-American Airlines ((||+1-877-590-0011)) or ((||+1-877-590-0011)) OTA (Live Person). When you call, you’ll be prompted to select options that direct you to the appropriate department, but be patient—there is always a way to reach a live person.