Tramadol, 50mg (pill imprint A 627) is a prescription painkiller that is identified as an opioid analgesic. It is commonly prescribed for managing moderate or moderately extreme discomfort.Activating opioid receptors in order to lessen the sensation of pain. inhibiting the reuptake process of serotonin and norepinephrine and norepinephrine, both of which contribute to the relief of pain and may affect the mood.