Doctors prescribe Sildenafil medication to address male reproductive issues like erectile dysfunction. However, this active pharmaceutical ingredient carries some implications for people dealing with or are prone to heart issues that warrant careful consideration. Here are the four key reasons why sildenafil should be approached with caution in individuals with cardiovascular conditions: 4 Potential Risks of Sildenafil related to heart conditions: Hypotension: Sildenafil acts as a vasodilator (drugs that open your blood vessels to improve blood flow). This vasodilation process leads to a decrease in blood pressure. For individuals with existing heart conditions, particularly those on medications like nitrates, this can result in clinically significant hypotension (low blood pressure), potentially leading to serious cardiovascular events. Cardiovascular Events: While there are some studies suggesting that sildenafil is generally safe for men with coronary artery disease (CAD). On the contrary, there have been isolated reports of myocardial infarction (tissue death) & sudden cardiac death associated with Sildenafil use. This risk is particularly concerning for people with severe underlying heart disease. Arrhythmias: There are concerns that sildenafil may increase the risk of fatal arrhythmias (irregular heart rhythms) in individuals with pre-existing cardiovascular disease. Although the overall incidence of serious cardiovascular adverse effects appears low, the potential for arrhythmias remains a consideration. Increased Cardiac Workload: Sildenafil can cause small decreases in both systolic and diastolic blood pressure, which may lead to an increase in heart rate and myocardial oxygen demand. For people with compromised cardiac function, this could exacerbate their condition. In conclusion, although sildenafil is effective for both pulmonary arterial hypertension and erectile dysfunction, it is not recommended to take in CVS-related conditions because of safety issues and the obvious lack of therapeutic benefits. Patients should speak with their healthcare provider for proper guidance on whether to take sildenafil for heart conditions or not. Additionally, since generic sildenafil, like Cenforce Oral Jelly (i.e., sildenafil citrate oral jelly)for erectile dysfunction treatment, is far less expensive than brand-name, go with it. Seek out any discounts offered by the drug maker or your online/offline pharmacy to save money. See your doctor: Prescription medicine cost-sharing schemes or alternatives may be recommended by your doctor.