Oxycontin OC 5 mg is the initial dose for patients who are not opioid-tolerant. This is the smallest dose of Oxycontin OC medicines. Its highest dose is Oxycontin OC 80 mg. Take this medication as directed by your doctor regularly. You should take this drug with or without food every 12 hours. Your doctor may increase the dose that is dependent on the severity of the pain.