Drinking alcohol while taking Oxycodone 10 mg can be deadly. Oxycodone is an opioid medication. If you feel any serious side effects then do not take this medicine and consult your doctor immediately. Talk to your doctor if you are going through other medicinal processes like Xanax, Klonopin, Valium, Ativan, Restoril, Zolpidem, or any other medication while taking this.