In the treatment of chronic nerve pain, epilepsy, or anxiety disorders, two drugs are generally used most of the time, which are Gabapentin and Pregabalin. Both drugs belong to the same class and share the same mechanism of action but exhibit variations in their efficacy, side effects, and usage. Both Gabapentin and Pregabalin are highly effective, and Gabapentin is more effective in pain reduction than Pregabalin.