Opana ER 30 mg is prescribed to treat average to severe pain or chronic severe pain. This is an opioid medication. This can be abused and it’s a highly addictive medicine. Opana ER extended tablets are available in different doses, such as 5 mg, 7.5 mg, 10 mg, 15 mg, 20 mg, 30 mg, and 40 mg. The composition of Hydrochloride per tablet determines the strength of the tablets.