Ambien is the brand name for zolpidem, a prescription medication used to treat insomnia—specifically, trouble falling asleep. It belongs to a class of drugs known as sedative-hypnotics. Ambien affects the brain to produce a calming effect by enhancing the activity of GABA, a neurotransmitter that slows brain activity. Forms: Immediate-release (helps you fall asleep faster) Extended-release (Ambien CR – helps you fall and stay asleep) Common brand names: Ambien, Ambien CR, Edluar, Intermezzo, Zolpimist