Oxycodone detox is a process where people stop using oxycodone under medical supervision to remove oxycodone from the body in a safe way. Detox is the most important part of the treatment process. It helps with Oxycodone Addiction Treatment for long-term recovery and building a healthy life. One of the risks of using oxycodone is that an individual can become physically dependent on it. Dependence can occur when a person relies on the oxycodone and continues to take it until their body gets used to it. Those who develop dependence may experience cravings and withdrawal symptoms when the drug is not being taken.