In the world, there are many opioids used to manage severe pain during some operations. Fentanyl is one of those opioids that is man-made but it is drastically more potent compared to the other opioids it is highly addictive. Many individuals are exposed to fentanyl without their knowledge, as it is widely available. It is impossible to detect by sight, smell, or taste. The risk of accidental overdose is exceptionally high. In this article, we will break down the chemical and systemic reasons why fentanyl is so dangerous, currently circulating.