Ambien (zolpidem) and Lunesta (eszopiclone) are sedative-hypnotics for insomnia. Ambien works quickly and is often used for sleep onset, while Lunesta lasts longer, helping with both falling and staying asleep. Lunesta may cause a bitter taste; Ambien is more linked to sleepwalking behaviors. Both can cause dependence, dizziness, and next-day drowsiness. Choice depends on sleep pattern, tolerance, and individual response under medical guidance.