Focalin contains dexmethylphenidate, a more focused form of methylphenidate, used to treat Attention Deficit Hyperactivity Disorder with fewer inactive components. Adderall combines amphetamine salts, often producing stronger, longer-lasting stimulation. Both improve attention and focus but can cause insomnia, appetite loss, and increased heart rate. Adderall may feel more potent, while Focalin can offer smoother effects for some individuals.