Gabapentin and Pregabalin are similar, but pregabalin is often considered more potent, faster-acting, and better absorbed. Gabapentin is cheaper and widely used but has variable absorption. Both treat nerve pain, seizures, and anxiety-related conditions. Pregabalin may cause more pronounced side effects like dizziness and weight gain, while gabapentin is sometimes better tolerated. Choice depends on response, cost, and medical guidance.