Gabapentin and Xanax serve different purposes, so “better” depends on the condition. Gabapentin treats nerve pain and seizures, sometimes anxiety, with lower dependence risk. Xanax is a fast-acting benzodiazepine for acute anxiety or panic, but carries higher risks of sedation, tolerance, and addiction. Gabapentin acts slower but is safer long-term; Xanax is more effective short-term under strict medical supervision.