Oxycodone is a prescription opioid used to manage certain types of moderate to severe pain. Because it can cause dependence, misuse, overdose, and other serious health problems, oxycodone is subject to strict regulations in many countries. This often raises an important question: Can you buy oxycodone online? The short answer is that oxycodone may be available through legitimate online pharmacies in some locations, but generally only with a valid prescription from an authorized healthcare professional. Websites offering oxycodone without requiring a prescription should be treated with extreme caution.