About CLICK HERE TO START YOUR SHOPPING Oxycodone is a prescription opioid medication used to manage certain types of moderate to severe pain when other treatments may not provide adequate relief. Because it can cause serious side effects, dependence, misuse, and potentially life-threatening breathing problems, oxycodone should only be used under the supervision of a qualified healthcare professional. The appropriate strength and dosage depend on the patient’s medical condition, treatment history, and individual response.