Watson 853 is a yellow, egg-shaped pill marked with 'WATSON 853,' which combines hydrocodone bitartrate (10 mg) and acetaminophen (325 mg). This prescription pain medication is designed to alleviate moderate to severe lower back pain. Hydrocodone serves as a strong opioid pain reliever for chronic conditions, while acetaminophen is a milder pain reliever that boosts the effectiveness of hydrocodone in the patients.