A test-tube baby is a normal child who is conceived by In Vitro fertilization. IVF is in which the word “vitro” means glass. The fertilization had done outside the uterus in a glass vessel test-tube by incorporating a female egg with a male sperm. Test-tube babies and in vitro fertilized babies are the same with no difference at all. Overview of IVF babies An egg is inseminated by injecting a single sperm into the egg or combining the egg with sperm in a petri-dish. Many babies are being born using IVF, IUI and they are healthy as normal babies. This protocol doesn't pose any term risk to the health of the baby. The difference between IVF babies and normal babies is the way in which they are originated. The researchers, scientists found that birth defects with an ivf infants were significantly raised, when we compare with the naturally conceived infants. Despite controlling for maternal factors. Clearly, test-tube babies would have greater rates of abnormality of the eye, heart.